RecruitingNCT05293470

A Post Marketing Surveillance on Piqray in Korea

A Post Marketing Surveillance on Piqray (Alpelisib) in Korea


Sponsor

Novartis Pharmaceuticals

Enrollment

900 participants

Start Date

Jun 29, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This is a prospective, multicenter, open-label, non-comparative, non-interventional, observational study to assess te safety and effectiveness of Piqray in the real-world setting


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria4

  • Subjects eligible for this study must meet all of the following criteria:
  • Postmenopausal women and men who have a confirmed diagnosis of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA mutated, advanced or metastatic breast cancer.
  • Patients who have progressed on prior endocrine based therapy and are going to start Piqray treatment for the first time in accordance with the locally approved label.
  • Patients who are willing to provide written informed consent

Exclusion Criteria6

  • Subjects eligible for this study must not meet the following criteria:
  • Patients with contraindication according to prescribing information for Piqray in Korea.
  • \- Severe hypersensitivity to Piqray or to any of its components
  • Female subjects who are pregnant and nursing (lactating)
  • Patients who are sexually active but not willing to follow contraceptive precautions during taking Piqray.
  • Participants who receive or are going to receive any investigational medicine during surveillance period.

Interventions

OTHERPiqray

There is no treatment allocation. Patients administered Piqray by prescription will be enrolled.


Locations(17)

Novartis Investigative Site

Cheonan Si, Chungcheongnam-do, South Korea

Novartis Investigative Site

Daegu, Dalseo gu, South Korea

Novartis Investigative Site

Deogyang Gu Goyang Si, Gyeonggi-do, South Korea

Novartis Investigative Site

Suwon, Gyeonggi-do, South Korea

Novartis Investigative Site

Gyeonggi-do, Korea, South Korea

Novartis Investigative Site

Busan, South Korea

Novartis Investigative Site

Busan, South Korea

Novartis Investigative Site

Daegu, South Korea

Novartis Investigative Site

Daejeon, South Korea

Novartis Investigative Site

Jeollanam, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

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NCT05293470


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