RecruitingNot ApplicableNCT05294445

From the Emergency Department Directly to Ablation of Atrial Fibrillation Study

From the Emergency Department Directly to Ablation of Atrial Fibrillation - Study - The "EMERGE-Cryo-Study"


Sponsor

Asklepios proresearch

Enrollment

350 participants

Start Date

Dec 15, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The study is a prospective, two-arm, randomized, open-label, blinded endpoint, multi-center study to investigate the impact of first line ablation in patients presenting at the emergency room with recent-onset paroxysmal or persistent atrial fibrillation.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether it's safe and effective to perform catheter ablation (a procedure that uses energy to correct the abnormal electrical signals causing atrial fibrillation) directly from the emergency department, without the usual wait for a scheduled outpatient appointment. **You may be eligible if...** - You are 18 or older - You have documented atrial fibrillation (AF) that is paroxysmal (comes and goes) or short-term persistent (episodes under 6 months) - Your AF started within the last year - You recently visited the emergency department or an outpatient clinic for AF within the past 2 weeks **You may NOT be eligible if...** - You have had AF continuously for more than 6 months - Your left atrium (a heart chamber) is very enlarged (diameter > 60mm) - You have severe mitral valve disease or have had prior mitral valve surgery - You have had a previous left heart ablation procedure - You are currently on amiodarone (a heart rhythm drug) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREAblation of atrial fibrillation (AF)

Cryo-AF-ablation of pulmonary vein (pulmonary vein isolation = PVI)


Locations(13)

Asklepios Klinik St. Georg

Hamburg, Free and Hanseatic City of Hamburg, Germany

Universitäres Herz- und Gefäßzentrum

Hamburg, Free and Hanseatic City of Hamburg, Germany

Kerckhoff-Klinik GmbH

Bad Nauheim, Germany

Deutsches Herzzentrum der Charité

Berlin, Germany

Herzzentrum Uniklinik Köln

Cologne, Germany

Evangelisches Krankenhaus Düsseldorf

Düsseldorf, Germany

Cardioangiologisches Zentrum Bethanien (CCB) am Markuskrankenhaus

Frankfurt, Germany

Universitätsklinikum Giessen

Giessen, Germany

AK Altona

Hamburg, Germany

AK Nord

Hamburg-Nord, Germany

Asklepios Klinik Harburg

Harburg, Germany

Universitätsklinikum Münster

Münster, Germany

St. Josefs-Hospital Wiesbaden GmbH

Wiesbaden, Germany

View Full Details on ClinicalTrials.gov

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NCT05294445


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