RecruitingNCT05303896

Investigating Myocardial Remodelling in the Failing Human Heart

Sponsor

Oslo University Hospital

Enrollment

200 participants

Start Date

May 30, 2022

Study Type

OBSERVATIONAL

Conditions

Heart Failure

Summary

Despite improvements in therapy, heart failure is a disease with high mortality and accelerating prevalence. To improve patient care, it is necessary to better understand the features and underlying mechanisms of myocardial remodeling; how it manifests in vivo and its underlying cellular and extracellular changes. The RELAX study will offer insight into myocardial remodeling, by comprehensively assessing function and structure of failing human hearts, and investigate its underlying cellular and extracellular changes.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This research study collects heart tissue samples from patients receiving a heart transplant to study how the failing heart changes at a cellular level (a process called myocardial remodelling). The findings may help scientists develop better treatments for heart failure in the future. **You may be eligible if...** - You are 18 or older - You are listed and eligible for a heart transplant - You are willing to participate and can sign the consent form **You may NOT be eligible if...** - You are under 18 years old - You are not willing or able to provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Oslo University Hospital

Oslo, Oslo, Norway

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NCT05303896

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