RecruitingPhase 1NCT05322213

THC Effects on Glucose in Type 2 Diabetes

The Effects of THC on Glucose Metabolism and Endothelial Function in Subjects With Type 2 Diabetes

Sponsor

University of California, San Diego

Enrollment

30 participants

Start Date

Aug 22, 2024

Study Type

INTERVENTIONAL

Conditions

Type 2 Diabetes

Summary

This study will examine the effects THC has on Glucose Metabolism and Endothelial Functioning in participants with Type 2 Diabetes. The participants will complete blood tests and tests to measure energy expenditure, CVD risks, and glucose metabolism. These tests will be performed prior to start of treatment and again after 2-weeks of treatment with the THC or placebo.

Eligibility

Min Age: 21 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study investigates how THC (the active ingredient in cannabis/marijuana) affects blood sugar levels in people with Type 2 diabetes, to better understand whether cannabis use has meaningful effects on glucose control. **You may be eligible if...** - You have been diagnosed with Type 2 diabetes - You are 21 or older - You are willing to use a controlled dose of THC under supervision during the study **You may NOT be eligible if...** - You have Type 1 diabetes - You are pregnant or breastfeeding - You have a history of psychosis or cannabis use disorder - You use insulin Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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