RecruitingPhase 3NCT05323149

Tranexamic Acid in Traumatic Brain Injury

The Impact of Early Use of Tranexamic Acid in Traumatic Brain Injury Upon the Inflammatory Response and Outcome

Sponsor

Assiut University

Enrollment

60 participants

Start Date

May 18, 2022

Study Type

INTERVENTIONAL

Conditions

Inflammatory Response

Summary

In this study, our aim is to investigate the role of tranexamic acid for modulating the inflammation in patients with traumatic brain injury (TBI).

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Saline and a drug called Tranexamic acid for people with inflammatory response. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSaline

Giving saline (loading dose of 1gm of saline 0.9%, followed by a 1gm of maintenance saline dose over 8 hours for 48 h).

DRUGTranexamic acid

Giving TXA (loading dose of 1gm of TXA, followed by a 1gm of maintenance dose over 8 hours for 48 h).

Locations(1)

Assiut university hospital

Asyut, Assuit, Egypt

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NCT05323149

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