RecruitingNot ApplicableNCT05326750

Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases


Sponsor

Kuopio University Hospital

Enrollment

200 participants

Start Date

Nov 21, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Double blinded, sham-controlled, randomized trial on repeated transcranial alternating current brain stimulation (tACS) in neurodegenerative diseases. The investigators will evaluate whether a 4-times daily repeated stimulation with gamma tACS on the posterior parietal cortex can improve symptoms in patients with neurodegenerative diseases, including dementia with Lewy Bodies, Alzheimer's disease, idiopathic normal pressure hydrocephalus and Frontotemporal dementia.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing non-invasive brain stimulation as a tool to help diagnose and manage neurodegenerative diseases like Alzheimer's and dementia. **You may be eligible if...** - You have mild cognitive impairment due to Alzheimer's disease - You have Dementia with Lewy Bodies - You have frontotemporal dementia - You have idiopathic normal pressure hydrocephalus (a type of brain fluid buildup) - You are 18 years or older **You may NOT be eligible if...** - You have a history of seizures - You are pregnant - You have metal implants in your head (dental fillings are okay) - You have an electronic implant such as a pacemaker or medical pump Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEGamma tACS (40 Hz) over the superior parietal cortex

Single session of gamma tACS (40 Hz) over the superior parietal cortex


Locations(1)

Kuopio University Hospital

Kuopio, Finland

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NCT05326750


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