RecruitingPhase 2NCT05335070

Reducing Pain From Wisdom Molar Extractions

Non-randomized Prospective Pilot Study on Effect of Temporo-masseteric Nerve Block (TMNB) on Pain Reduction Following Wisdom Molar Extractions

Sponsor

Rutgers, The State University of New Jersey

Enrollment

20 participants

Start Date

Sep 13, 2022

Study Type

INTERVENTIONAL

Conditions

Acute Pain

Summary

This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third molar(s) under intravenous sedation. Study participants will be queried for pain experience and pain medications taken during the first post-operative week and will present for a follow-up visit on Day 8.

Eligibility

Min Age: 18 YearsMax Age: 64 Years

Inclusion Criteria6

Age 18 years of age or older (up to 64 years)
Any demographic
ASA 1 and 2 (mild or absent systemic illnesses, deemed fit for undergoing dental extractions under intravenous sedation)
Not pregnant (as will not qualify to undergo procedure under intravenous sedation as part of routine standard-of-care)
Adequate mental ability to understand and provide informed consent
Has smart phone and internet connection

Exclusion Criteria7

Age older than 64 years (because they are poor candidates for undergoing procedures under intravenous sedation)
Pregnant
Incapable of providing informed consent
Any systemic condition that renders the patient at higher risk for complications under intravenous sedation
Documented allergy to the dental local anesthetic
Inability to tolerate any of the commonly used pain medications such as combination opioids, acetaminophen (Tylenol®) or ibuprofen (Motrin® or Advil®)
Limitation in adequate mouth opening in presence/absence of pain

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGTemporo-masseteric Nerve Block

Following lower third molar extraction under intravenous sedation, the patient will receive the TMNB local anesthetic nerve block using the standard dental local anesthetic, i.e,. 2% lidocaine with 1:100,000 epinephrine on the side/s of the lower wisdom molar (third molar) extraction/s