RecruitingNCT05336890

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age


Sponsor

Ann & Robert H Lurie Children's Hospital of Chicago

Enrollment

500 participants

Start Date

Nov 1, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Early detection and intervention are critical to mitigate the impact of these impairments. Mechanisms leading from premature birth to these undesirable outcomes remain unclear, and accurate prognostic measures are lacking. This study wants to learn if these problems are related to certain patterns of breathing that babies had while they were in the NICU.


Eligibility

Min Age: 30 WeeksMax Age: 83 Months

Plain Language Summary

Simplified for easier understanding

This study is following up on premature babies who were part of an earlier study (Pre-Vent) to understand how episodes of low oxygen levels in the NICU affect their development and health when they reach preschool age. **You may be eligible if...** - Your child was previously enrolled in the Pre-Vent research study - Your child was born before 29 weeks of pregnancy - Your child is under 7 years old at the time of enrollment **You may NOT be eligible if...** - Your child was withdrawn from the Pre-Vent study - No physiological data was recorded for your child in Pre-Vent - Local regulations or your family's preferences do not allow re-contact - Your child was enrolled at Washington University St. Louis (not a participating site) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States

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NCT05336890


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