RecruitingNCT05340023

Proteomic Pattern Associated With the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension

Proteomic Pattern Associated With the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension : PROTEO-CTEPH Study.


Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Enrollment

120 participants

Start Date

Nov 9, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Chronic ThromboEmbolic Pulmonary Hypertension (CTEPH) is a rare but severe complication of pulmonary embolism (PE). CTEPH is evoked in patients with persistent dyspnea. According to international guidelines, symptomatic patients with perfusion defects on lung scan and Pulmonary Hypertension (PH)-likely transthoracic echo (TTE) must be evaluated in Pulmonary Hypertension (PH)-centers with right heart catheterism, to confirm or rule out the presence of precapillary Pulmonary Hypertension (PH), and precise the group of Pulmonary Hypertension (PH).


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Patient with a suspicion of Chronic thromboembolic pulmonary hypertension (CTEPH) with a combination of a perfusion lung scan and transthoracic perfusion scan and transthoracic echocardiography compatible with the diagnosis (according to French recommendations)
  • Patients who require a right heart catheterization.
  • Patient affiliated or entitled to a social security plan
  • Patient having received informed information about the study informed about the study

Exclusion Criteria2

  • Patient with a normal perfusion lung scan
  • Person under legal guardianship

Interventions

BIOLOGICALblood sample

to realize proteomic analysis.


Locations(1)

CHU de SAINT-ETIENNE

Saint-Etienne, France

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NCT05340023


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