Biocollection of Patients With ANCA Associated Vasculitis
Biocollection of Patients With ANCA Associated Vasculitis Diagnosed Within the CERAINO Autoimmune Disease Reference Center, Part of the Global BRAISE Project (B-dependent Rare AutoImmune DiseaSES
University Hospital, Brest
100 participants
Oct 27, 2022
INTERVENTIONAL
Conditions
Summary
As rare disease, vasculitis affects a small number of patients, the cohorts available in the literature are few and the pathophysiological mechanisms remain to be elucidated. The collection of standardized data within a patientheque as part of a multi-year follow-up will facilitate the study of the characteristics of these diseases. This may, in particular, address the main objective of identifying predictors of relapse, as well as secondary objectives for predictive factors of mortality, infectious, cardiovascular or neoplastic complications that affect the prognosis of vasculitis in order to establish a more appropriate management of the patients concerned.
Eligibility
Inclusion Criteria5
- Major patients with no upper age limit.
- Patients assessed as part of the reference centre for rare autoimmune diseases at the CHRU in Brest.
- Patients for whom a diagnosis of ANCA-associated vasculitis is made by the physician in charge of the patient, according to the definitions of the Chapel-Hill Consensus Conference.
- Patient affiliated with Social Security
- Patient who has signed written informed consent
Exclusion Criteria6
- Minor
- Patients unable to consent.
- Patients refusing to participate in research
- Patient under legal protection (tutelage, curatorship)
- Pregnant or lactating women
- Hemoglobin (Hb) < 7g/dL
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Interventions
Blood samples (80 mL) at inclusion, once a year for 5 years, and if relapse or change of treatment
Fecal samples at inclusion
Urinary samples at inclusion, once a year for 5 years, and if relapse or change of treatment
Questionnaires at inclusion, once a year for 5 years, and if relapse or change of treatment
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05364892