RecruitingEarly Phase 1NCT05364970

IVR in Motor Rehabilitation

Immersive Virtual Reality in the Rehabilitation of Peripheral Injuries


Sponsor

University of Turin, Italy

Enrollment

45 participants

Start Date

Apr 12, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The present project on sport rehabilitation aims at validating a rehabilitation protocol in immersive virtual reality (IVR) for restoring motor functions following peripheral injuries of the lower limbs. Sport injuries are related to direct and indirect costs and, in many cases, cause an interruption of motor activity for prolonged periods. Sport physiotherapy aims at recovering the motor functionality in order to guarantee the fastest possible return to sport. It employs plasticity and compensatory mechanisms within the injured motor system. However, being primarily based on the execution of movements that can be largely compromised, the treatment might be intrinsically complicated. It has been suggested that the motor system can be activated by observing one's own body perform the movements, without any actual movement execution. By using multisensory integration and sense of presence in IVR, it is possible to create an illusory experience that a moving virtual body (avatar) temporarily becomes one's own moving body. Moreover, this experience activates the motor system similarly to the activation from one's own actual movements. Based on these considerations, the present study hypothesizes that observation of one's own virtual body, without any movement execution, might activate the motor system to the extent of significantly improving functional recovery. The randomized clinical trial will recruit participants that underwent knee surgery and are in the first phase of the rehabilitation period (starting within two weeks after the surgery). Together with the traditional training protocol (4-6 weeks) participants will be administered a training in IVR that will include a virtual avatar performing a series of standard lower limb rehabilitation exercises. Participants will be randomly assigned to the experimental group (avatar observed from the first-person perspective, i.e., perceived as one's own body), the active control group (avatar observed from the third-person perspective, i.e., perceived as another person's body) and the group with no intervention. Before, at midpoint and after intervention, a standard battery of tests will be administered to evaluate the state of the motor system), as well as measures of embodiment for controlling the efficacy of the virtual scenario. The hypothesis is that the experimental group will show greater improvement of the motor functionality compared to the two control groups.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether watching a virtual reality (VR) avatar perform rehabilitation exercises from a first-person perspective (as if the movements were your own) can help improve recovery from knee surgery without requiring physical movement. The approach is based on evidence that simply observing your own body move activates the same brain systems involved in real movement. You may be eligible if you are 18 to 65 years old, have recently undergone knee surgery for a sprain, ligament tear, or meniscus injury, and do not have a history of neurological conditions or severe motion sickness with VR. Participation involves twice-weekly VR training sessions over 6 weeks alongside your standard physiotherapy program, with movement and function tests at the start, middle, and end of the study. This summary was prepared using AI to help patients understand this research.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

COMBINATION_PRODUCTVR_Training_1PP

Immersive VR scenario of physical training with avatar embodiment

COMBINATION_PRODUCTVR_Training_3PP

Immersive VR scenario of physical training without avatar embodiment


Locations(1)

University of Turin

Turin, TO, Italy

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NCT05364970


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