RecruitingNCT05366153

Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer

Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer (REDEEM-CAD)


Sponsor

Baker Heart and Diabetes Institute

Enrollment

748 participants

Start Date

Oct 18, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

REDEEM-CAD is a prospective multi-centre study of CAD risk evaluation and management in cancer survivors 40-70 years with chemotherapy or radiotherapy \>5 years ago.


Eligibility

Min Age: 40 YearsMax Age: 70 Years

Inclusion Criteria1

  • A history of cancer >5 y ago associated with potential cardiotoxicity from chemotherapy and/or radiotherapy (chiefly survivors of breast cancer, Hodgkin's lymphoma and prostate cancer).

Exclusion Criteria6

  • Unable to provide written informed consent to participate in this study
  • Known coronary artery disease at recruitment
  • History of previous coronary artery disease
  • Inability to acquire interpretable CT images
  • Contraindications/Intolerance to or already taking statin therapy
  • Oncologic (or other) life expectancy <12 months or any other medical condition (including pregnancy) that results in the belief (deemed by the Chief Investigators) that it is not appropriate for the patient to participate in this trial

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Interventions

DIAGNOSTIC_TESTCoronary CT

Screening/Management Plan


Locations(2)

Tom Marwick

Hobart, Tasmania, Australia

Baker Heart and Diabetes Institute

Melbourne, Victoria, Australia

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NCT05366153


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