RecruitingNot ApplicableNCT05366647

GATT Versus Canaloplasty (GVC)

Longterm Comparison of Gonioscopy-assisted Transluminal Trabeculotomy and Canaloplasty in Open-angle Glaucoma Treatment


Sponsor

Medical University of Bialystok

Enrollment

100 participants

Start Date

Jun 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Study aims to compare the effectiveness and safety profile of Gonioscopy-assisted Transluminal Trabeculotomy and canaloplasty, in order to find out if one operation is superior to the other. Both procedures are performed in patients with medically uncontrolled open-angle glaucoma. Canaloplasty is a recently newly introduced procedure, which showed encouraging results without antimetabolite usage intra- and postoperatively. Gonioscopy-assisted Transluminal Trabeculotomy is the procedure that aims the same mechanism of aqueous outflow, however is perform with ab interno approach, which comprise it to the minimally invasive glaucoma surgery techniques. Purpose of the study is to compare both surgeries concerning success rate, intraocular pressure, medication burden and complications rate. So far there is no comparison of the Gonioscopy-assisted Transluminal Trabeculotomy and canaloplasty available.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Years and older (Adult, Older Adult)
  • patients with confirmed uncontrolled open angle glaucoma
  • no prior glaucoma surgery (once laser trabeculoplasty or cyclophotocoagulation) allowed

Exclusion Criteria3

  • angle closure glaucoma
  • congenital glaucoma
  • inflammatory glaucoma

Interventions

PROCEDUREcanaloplasty

canaloplasty ab interno with tensioning suture

PROCEDUREGonioscopy-assisted Transluminal Trabeculotomy

Gonioscopy-assisted Transluminal Trabeculotomy ab interno


Locations(1)

Ophthalmology Clinic Medical University of Bialystok

Bialystok, Poland

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NCT05366647


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