RecruitingNot ApplicableNCT05366647

GATT Versus Canaloplasty (GVC)

Longterm Comparison of Gonioscopy-assisted Transluminal Trabeculotomy and Canaloplasty in Open-angle Glaucoma Treatment


Sponsor

Medical University of Bialystok

Enrollment

100 participants

Start Date

Jun 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Study aims to compare the effectiveness and safety profile of Gonioscopy-assisted Transluminal Trabeculotomy and canaloplasty, in order to find out if one operation is superior to the other. Both procedures are performed in patients with medically uncontrolled open-angle glaucoma. Canaloplasty is a recently newly introduced procedure, which showed encouraging results without antimetabolite usage intra- and postoperatively. Gonioscopy-assisted Transluminal Trabeculotomy is the procedure that aims the same mechanism of aqueous outflow, however is perform with ab interno approach, which comprise it to the minimally invasive glaucoma surgery techniques. Purpose of the study is to compare both surgeries concerning success rate, intraocular pressure, medication burden and complications rate. So far there is no comparison of the Gonioscopy-assisted Transluminal Trabeculotomy and canaloplasty available.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two surgical procedures for treating open-angle glaucoma (a condition where eye pressure damages the optic nerve): GATT (a newer procedure that opens the eye's drainage channel) versus canaloplasty (a procedure that widens the drainage channel). Both aim to lower eye pressure without a traditional trabeculectomy. **You may be eligible if...** - You are 18 years or older - You have confirmed open-angle glaucoma that is not adequately controlled - You have not had previous glaucoma surgery (one prior laser treatment is acceptable) **You may NOT be eligible if...** - You have angle-closure glaucoma (a different type) - You have congenital glaucoma (present from birth) - You have inflammatory glaucoma (caused by eye inflammation/uveitis) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREcanaloplasty

canaloplasty ab interno with tensioning suture

PROCEDUREGonioscopy-assisted Transluminal Trabeculotomy

Gonioscopy-assisted Transluminal Trabeculotomy ab interno


Locations(1)

Ophthalmology Clinic Medical University of Bialystok

Bialystok, Poland

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05366647


Related Trials