Glaucoma, Open-Angle Clinical Trials

23 recruiting

Frequently Asked Questions

Common questions about Glaucoma, Open-Angle clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting
Phase 4

Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone

Glaucoma, Open-AngleOcular Hypertension (OHT)Phacoemulsification Cataract Surgery
Glaukos Corporation132 enrolled1 locationNCT06848946
Recruiting
Phase 3

Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone

Glaucoma, Open-Angle
Glaukos Corporation230 enrolled1 locationNCT06066645
Recruiting
Not Applicable

Feasibility Clinical Evaluation of the Calibreye System

Glaucoma, Open-Angle
Myra Vision Inc.60 enrolled4 locationsNCT05885022
Recruiting
Not Applicable

Electrical Stimulation for Vision Neuroenhancement in Glaucoma

GlaucomaGlaucoma, Open-Angle
Stanford University30 enrolled1 locationNCT06685211
Recruiting
Not Applicable

Clinical Study Evaluating the Efficacy and Safety of CID v2.2 in Glaucoma Surgery

Glaucoma, Open-AngleGlaucoma, Narrow Angle
Ciliatech29 enrolled6 locationsNCT05625958
Recruiting
Not Applicable

SCTSC Versus Trabeculectomy in Medically Uncontrolled Open-Angle Glaucoma in Pseudophakic Patients

Glaucoma, Open-Angle
Minia University50 enrolled1 locationNCT07152132
Recruiting
Not Applicable

Feasibility, Accuracy, and Reproducibility of Virtual Reality Visual Field Testing in Patients With Glaucoma

Glaucoma, Open-Angle
Nova Scotia Health Authority60 enrolled1 locationNCT07063537
Recruiting
Not Applicable

Electrical Stimulation for the Treatment of Optic Neuropathies

GlaucomaGlaucoma, Open-AngleOptic Nerve Diseases
Stanford University40 enrolled1 locationNCT05626426
Recruiting
Not Applicable

Transscleral Selective Laser Trabeculoplasty Project

Glaucoma, Open-AngleOcular Hypertension (OH)
Lumibird Medical (Quantel Medical, Ellex Medical, Optotek)15 enrolled1 locationNCT06833060
Recruiting
Not Applicable

Optic Nerve Head Strain as Biomarker for Glaucoma

Glaucoma, Open-Angle
Johns Hopkins University130 enrolled1 locationNCT06240312
Recruiting
Phase 2

Evaluate Efficacy and Safety of PA5108 Ocular Implants in Primary Open Angle Glaucoma or Ocular Hypertension

Ocular HypertensionGlaucoma, Open-Angle
PolyActiva Pty Ltd75 enrolled1 locationNCT06964191
Recruiting

24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring

GlaucomaOcular HypertensionGlaucoma, Open-Angle+8 more
Smartlens, Inc.125 enrolled3 locationsNCT06689696
Recruiting
Not Applicable

Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects

Ocular HypertensionNormal Tension GlaucomaGlaucoma, Open-Angle
Medical University of Vienna120 enrolled1 locationNCT03870230
Recruiting
Not Applicable

A Trial of Hydrus Microstent Versus Goniotomy

GlaucomaGlaucoma, Open-Angle
Massachusetts Eye and Ear Infirmary243 enrolled1 locationNCT06289491
Recruiting
Not Applicable

GATT Versus Canaloplasty (GVC)

Glaucoma, Open-Angle
Medical University of Bialystok100 enrolled1 locationNCT05366647
Recruiting

Dresden Glaucoma and Treatment Study (DGTS)

GlaucomaGlaucoma, Open-AngleGlaucoma, Angle-Closure+1 more
Technische Universität Dresden10,000 enrolled1 locationNCT02959242
Recruiting
Not Applicable

Evaluation of Phacogoniotomy in Medically-controlled POAG

Glaucoma, Open-AngleCataract ComplicatedGoniotomy
Sun Yat-sen University100 enrolled1 locationNCT06201455
Recruiting
Not Applicable

Electrical Stimulation for the Treatment of Glaucoma

GlaucomaGlaucoma, Open-Angle
Stanford University45 enrolled4 locationsNCT05626491
Recruiting

Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical Prostaglandins

Ocular HypertensionGlaucoma, Open-Angle
Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA40 enrolled1 locationNCT05039684
Recruiting
Not Applicable

Results of Patients With Glaucoma Undergoing Minimally Invasive Glaucoma Surgery in Conjunction With Cataract Surgery

CataractGlaucoma, Open-Angle
Vold Vision P.L.L.C25 enrolled1 locationNCT05624398