South Asians and Coronary Plaque Registry
University of Texas Southwestern Medical Center
300 participants
Jun 15, 2022
OBSERVATIONAL
Conditions
Summary
Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The registry will serve to generate primary observations as well as preliminary data for future studies.
Eligibility
Inclusion Criteria4
- Males and Females: Age 18 years or above
- South Asian (SA) adults through self-identification (South Asians to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh)
- We also propose to enroll an equivalent number of individuals of other descent as a comparator group (Non SA Adult Volunteers)
- Sampling Method: Probability Sample
Exclusion Criteria8
- Under the age of 18 years
- Unable to give informed consent
- Impaired renal function: estimated glomerular filtration rate ≤ 45ml/min
- Baseline heart rate≥70 bpm or ≥66 bpm after beta blocker
- Body mass index (BMI) of 35 or greater
- Prior anaphylactic/non-anaphylactic reaction or other contraindication to iodinated contrast
- Anyone who cannot do CCTA for any reason
- Pregnancy
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Interventions
A computerized tomography (CT) coronary angiogram is non-invasive imaging test that looks at the arteries that supply blood to your heart.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05367297