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RecruitingNot ApplicableNCT05371977

Deep Sclerectomy Versus Trabeculectomy in Normal Tension Glaucoma

Sponsor

Helsinki University Central Hospital

Enrollment

80 participants

Start Date

May 31, 2022

Study Type

INTERVENTIONAL

Conditions

Normal Tension Glaucoma

Summary

The purpose of this study is to assess whether deep sclerectomy is as effective in lowering intraocular pressure (IOP) as trabeculectomy in patients with normal tension glaucoma.

Eligibility

Min Age: 55 YearsMax Age: 100 Years

Inclusion Criteria3

  • Signed Informed Consent
  • Normal Tension Glaucoma with typical nerve fiber layer defects in red-free photographs and/or optical coherence tomography (OCT) and possible equivalent visual field defects, IOP never more than 21 mmHg, and open anterior chamber angle
  • Glaucoma unstable with current medication assessed by a glaucoma specialist

Exclusion Criteria15

  • Secondary Glaucoma e.g. due to previous injury or uveitis
  • Exfoliation syndrome
  • Pigment dispersion syndrome
  • Previous transscleral or endoscopic cyclophotocoagulation
  • Previous other glaucoma surgery
  • Previous retinal detachment
  • Previous intraocular surgery like vitrectomy and other retinal surgery
  • Wet age-related macular degeneration
  • Diabetic retonopathy
  • Previous corneal transplant or previous refractive surgery
  • Fuchs' dystrophy and other abnormalities compromising corneal clarity like scars
  • The patient does not want to participate in the study
  • The patient does not speak Finnish, Swedish or English
  • Dementia
  • Only eye with vision worse than 20/200 or loss of central visual field

Interventions

PROCEDURETrabeculectomy

trabeculectomy glaucoma surgery

PROCEDUREDeep Sclerectomy

deep sclerectomy glaucoma surgery

Locations(1)

Helsinki University Central Hospital

Helsinki, Finland

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NCT05371977

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