RecruitingNot ApplicableNCT05372484

Rice Technologies for Cervical Cancer Screening and Diagnosis

Assessment of New Technologies for the Screening and Diagnosis of Cervical Cancer in Mozambique, A Study to be Conducted in Maputo Central Hospital, Mavalane and Jose Macamo General Hospitals and Mavalane Health Center

Sponsor

M.D. Anderson Cancer Center

Enrollment

678 participants

Start Date

Mar 24, 2021

Study Type

INTERVENTIONAL

Conditions

Cervical Cancer

Summary

The study aims to compare the accuracy of the lateral flow test to detect HPV at the POC with commercially available HPV test and to determine the diagnostic accuracy and reliability of a multimodal optical imaging system to detect cervical dysplasia, with the gold reference standard of histopathology.

Eligibility

Sex: FEMALEMin Age: 25 YearsMax Age: 49 Years

Plain Language Summary

Simplified for easier understanding

This study is testing new imaging and diagnostic tools developed by Rice University to improve how cervical cancer is screened and diagnosed. The goal is to evaluate whether these technologies work as well as or better than standard diagnostic procedures like colposcopy. **You may be eligible if...** - You are a woman between 25 and 49 years old - You have had an abnormal cervical screening result (abnormal Pap smear, positive HPV test, or abnormal VIA test) - Your cervix is intact (no prior hysterectomy) - You are not pregnant (confirmed by a pregnancy test within 14 days) and not currently breastfeeding **You may NOT be eligible if...** - You are under 25 or over 49 - You have had a total hysterectomy (removal of the cervix) - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEMultimodal optical imaging

Women referred for colposcopy due to abnormal cervical screening will be recruited into the experimental group of the study. Imaging of study participants will take place during the colposcopy examination.