Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy
Evaluating the Diagnostic Yield and Specimen Quality With Endobronchial Ultrasound-Guided Intranodal Forceps Biopsies in Patients With Mediastinal and Hilar Lymphadenopathy: A Prospective Analysis
George Washington University
55 participants
Jun 10, 2022
INTERVENTIONAL
Conditions
Summary
The investigators will compare endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) with intranodal forceps biopsy (EBUS-IFB) as it relates to the rate of diagnosis of suspected sarcoidosis.
Eligibility
Inclusion Criteria3
- Radiologic evidence of mediastinal and/or hilar lymphadenopathy
- Attending radiologist or pulmonologist reports a possible diagnosis of sarcoidosis
- Age 18 years or older
Exclusion Criteria11
- These are the characteristics that a participant must NOT have in order to be eligible to participate in the study.
- Order Number Criteria
- Severe pulmonary hypertension
- Inability to undergo general anesthesia
- Severe coagulopathy or bleeding diathesis
- Previously diagnosed sarcoidosis
- Patient presently taking clopidogrel
- Patient deemed to be high risk for general anesthesia per anesthesiologist
- Hemodynamic instability
- Mediastinitis
- Acute Hypercarbic Respiratory Failure (pCO2 >55mmHg)
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Interventions
Patients with mediastinal adenopathy will undergo EBUS-IFB and EBUS-TBNA during the same procedure to compare the yield of this procedure with EBUS-TBNA alone.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05374447