Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

This study is looking at whether a prostate MRI scan can serve as an early screening tool to detect prostate cancer in men who are at higher-than-average risk but have a PSA level that falls in a gray zone — low enough that a biopsy is not usually recommended, but not zero. The aim is to catch cancer earlier in high-risk men without over-testing everyone. **You may be eligible if...** - Your PSA (prostate-specific antigen) blood test result is between 1.0 and 2.5 ng/mL - You are at higher risk for prostate cancer because you are Black, have a father or brother with prostate cancer, or carry a relevant genetic mutation **You may NOT be eligible if...** - Your prostate feels abnormal on physical exam (nodules or firmness) - You have had a prior prostate biopsy or prostate surgery - You are taking finasteride or dutasteride (medications for enlarged prostate) - You are unable to have an MRI scan (e.g., due to a pacemaker or claustrophobia) Talk to your doctor to see if this trial is right for you.