RecruitingNCT05389774

DOLCE: Determining the Impact of Optellum's Lung Cancer Prediction Solution

DOLCE: Determining the Impact of Optellum's Lung Cancer Prediction (LCP) Artificial Intelligence Solution on Service Utilisation, Health Economics and Patient Outcomes


Sponsor

Nottingham University Hospitals NHS Trust

Enrollment

2,000 participants

Start Date

Mar 23, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This study is a multi-centre prospective observational cohort study recruiting patients with 5-30mm solid and part-solid pulmonary nodules that have been detected on CT chest scans performed as part of routine practice. The aim is to determine whether physician decision making with the AI-based LCP tool, generates clinical and health-economic benefits over the current standard of care of these patients.


Eligibility

Min Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether an AI-powered software tool called Optellum Lung Cancer Prediction (LCP) can help doctors make better decisions about small spots (nodules) found in the lungs on CT scans — predicting whether each nodule is likely cancerous, and thereby reducing unnecessary procedures while catching cancer earlier. **You may be eligible if...** - You are 35 or older - A CT scan incidentally found at least one solid or part-solid lung nodule (a small spot in the lung, not found due to symptoms) - Your nodule is being monitored or evaluated at the study site **You may NOT be eligible if...** - You have been diagnosed with any cancer in the past 5 years - You have metal implants in your chest that interfere with CT imaging quality - You have had previous lung surgery that would make nodule analysis unreliable Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(10)

Betsi Cadwaladr University Health Board

Bangor, United Kingdom

Frimley Health NHS Foundation Trust (Wexham Park Hospital)

Frimley, United Kingdom

Leeds Teaching Hospitals NHS Trust

Leeds, United Kingdom

King's College Hospital NHS Foundation Trust

London, United Kingdom

Royal Free Hospital

London, United Kingdom

St. George's University Hospitals NHS Foundation Trust

London, United Kingdom

The Royal Marsden NHS Foundation Trust

London, United Kingdom

University College London Hospitals NHS Foundation Trust

London, United Kingdom

Nottingham University Hospitals NHS Trust

Nottingham, United Kingdom

Oxford University Hospitals NHS Foundation Trust

Oxford, United Kingdom

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NCT05389774


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