RecruitingNCT05393609

Quality of Life and Surgery in Diverticular Disease


Sponsor

University of Aarhus

Enrollment

250 participants

Start Date

Apr 22, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Diverticular disease is one of the most common diseases of the gastrointestinal tract in industrial countries. Prevalence and admission rate due to diverticular disease increases. Symptomatic patients usually present with acute uncomplicated or complicated diverticulitis. Recurrence rates of complicated diverticulitis are estimated to 10-30%. Recurrences, chronic complications or persisting pain, here collectively referred to as chronic diverticular disease, may be treated by elective sigmoidectomy. Currently, there is no specific criteria for elective surgery, but only a recommendation of a tailored approach depending on the patient's symptoms. It is well established that diverticular disease has a negative impact on quality of life (QoL). Elective laparoscopic sigmoidectomy may increase QoL. In this prospective study, we will prospectively examine QoL, patient-related outcomes and peri- and postoperative outcome of elective sigmoidectomy for chronic diverticular disease, and compare it to conservatively treated patients.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Referred to surgical clinic due to diverticular disease
  • Colonic diverticula verified by CT or endoscopy

Exclusion Criteria6

  • Previous colonic resection other than appendectomy
  • Previous or current colorectal cancer
  • Previous or current disseminated cancer
  • Inflammatory bowel disease
  • Psychiatric disorder influencing the ability to answer questionnaires
  • Inadequate Danish

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Interventions

PROCEDURESigmoidectomy

Conventional laparoscopic resection of the sigmoid colon

DIETARY_SUPPLEMENTConservative

According to current practice including advice on supplementary dietary fiber, analgetics, or laxatives when indicated.


Locations(1)

Randers Regional Hospital

Randers, Central Jutland, Denmark

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