RecruitingNot ApplicableNCT06326905

CAPABLE Transplant

Addressing Inactive Kidney Transplant Waitlist Status Through Adapting a Tailored Psycho-Social-Environmental Program

Sponsor

Johns Hopkins University

Enrollment

43 participants

Start Date

Jan 25, 2025

Study Type

INTERVENTIONAL

Conditions

Quality of Life Disability Physical Depression End Stage Renal Disease

Summary

The purpose of this mixed methods study is to adapt CAPABLE as CAPABLE Transplant to accomplish two things: 1) To resolve barriers to being classified as active on the Kidney Transplant (KT) waitlist, 2) as a surgical prehabilitation intervention targeting the pre-frail/ frail KT waitlist population. It consists of two phases- an open label pilot and a randomized waitlist control trial, and 3) pilot test the feasibility and acceptability for CAPABLE Transplant in symptom and waitlist specific metrics amongst low-income active kidney transplant waitlist candidates.

Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This study (CAPABLE Transplant) helps people on the kidney transplant waiting list improve their health and readiness for transplant through a supportive program. CAPABLE combines occupational therapy, nursing visits, and home repairs to help older or low-income adults improve their physical function, safety, and overall wellbeing while waiting for a donor kidney. **You may be eligible if...** - You are 18 or older - You are on the deceased donor kidney transplant waiting list - You live in the community (not in a care facility) - You are currently inactive on the transplant list (or were inactive recently due to heart disease, frailty, obesity, mental health, or other reasons), OR you are active but have low income **You may NOT be eligible if...** - You are on the living donor transplant list - You have severe cognitive impairment - You are expected to be inactive for more than 3 months (e.g., due to ongoing cancer treatment) - You have been hospitalized 4 or more times in the past year - You already receive home nursing or therapy services Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCAPABLE Transplant- Open Label Pilot

As in CAPABLE, the delivery characteristics of CAPABLE Transplant consist of an assessment-driven, individually tailored package of interventions delivered over the course of 4 months by an occupational therapist (OT) (\~6 home visits for ≤ 1hour), a registered nurse (RN) (\~4 home visits for ≤ 1hour) and a handy worker (HW). Adaptations targeting those currently KT inactive will be made on a per-client basis as part of the open-label pilot. We will further refine and develop the intervention by receiving feedback from the open label pilot participants and CAPABLE clinicians who implemented the pilot to gain their perspective of the acceptability and feasibility of implementing the CAPABLE-Transplant intervention. Based on this feedback, the study team will have developed an adapted iteration of the prototype.

BEHAVIORALCAPABLE Transplant- Randomized Control Trial