RecruitingNCT05395598

Incidence of Major Complication in Case of Thoracic Aortic Aneurysm

Predicting Moderate Thoracic Aortic Aneurysm Evolution: a Longitudinal Study of Systemic Factors in Patients Free of Connective Tissue Disease. .

Sponsor

University Hospital, Lille

Enrollment

320 participants

Start Date

Apr 18, 2024

Study Type

OBSERVATIONAL

Conditions

Thoracic Aortic Aneurysm

Summary

Thoracic aneurysm is a silent disease with a potential mid-term high risk of death or major complications. Few data are available on the real incidence of major complications in case of small and moderate thoracic aneurysm. Different factors are supposed to increase the risk of aortic enlargement as high blood pressure and sleep disorder breathing. The modality of imaging and clinical follow-up are well defined. In this prospective observational study, the aim to assess the incidence of of major complications during follow-up in a population of patients with a small or moderate thoracic aneurysm. The study will also try to identify systemic factors influencing aneurysm evolution.

Eligibility

Min Age: 45 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is tracking people with an enlarged aortic root (the main blood vessel leaving the heart) over five years to understand how often serious complications occur and what factors predict them. **You may be eligible if...** - You have been diagnosed with an aortic root aneurysm larger than 40mm - You are willing to participate in regular follow-up visits over five years **You may NOT be eligible if...** - You have a serious illness with a life expectancy of less than one year - You have a personal or family history of a genetic connective tissue disorder (such as Marfan syndrome or Loeys-Dietz syndrome) - You have previously had surgery on your aorta Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

CHU Lille

Lille, Please Choose..., France

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NCT05395598

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