Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color
Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color: A Prospective, Randomized Split-wound Study
Melissa Pugliano-Mauro
34 participants
Oct 1, 2022
INTERVENTIONAL
Conditions
Summary
The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color. Through a split-wound study design, patients undergoing standard elliptical excisions at least 3 cm in length will receive each suture type. Measurements of dyspigmentation and scarring will be made at 7 days (for the head and neck), 10 days (for the trunk and extremities), and 3 months for all locations.
Eligibility
Inclusion Criteria5
- Age 18 years or older
- Undergoing dermatologic surgery with planned standard elliptical excision with wound length of 3 cm or greater. Benign and malignant lesions will be included, including those that have undergone Mohs micrographic surgery prior to standard linear closure. All body sites will be included.
- Able to give informed consent
- Able to return for 3 month follow up
- New Immigration Scale (NIS) skin color 4 or greater - The NIS is an 11 point scale, ranging from zero to 10, with zero representing albinism and 10 representing the darkest possible skin.
Exclusion Criteria3
- High-tension closures not amenable to 5-0 simple running epidermal sutures
- Known allergy to suture material
- Pregnant
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Interventions
Split-wound, intra-individual comparison - half of wound will receive 5-0 polypropylene epidermal suture and half of wound will receive 5-0 fast gut epidermal suture
Split-wound, intra-individual comparison - half of wound will receive 5-0 polypropylene epidermal suture and half of wound will receive 5-0 fast gut epidermal suture
Locations(3)
View Full Details on ClinicalTrials.gov
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NCT05408117