Urine HPV Testing for Cervical Cancer Screening Among Women Living With HIV in South Africa

This study is testing whether urine-based HPV testing can replace or supplement traditional cervical swab testing (Pap smear/cervical HPV test) for cervical cancer screening in women living with HIV in South Africa. Women with HIV have higher cervical cancer risk. **You may be eligible if...** - You have confirmed HIV-1 infection - You are 25 years of age or older - You have not had cervical cancer screening in the past year - You are willing and able to provide written consent **You may NOT be eligible if...** - You are pregnant or plan to become pregnant within 90 days - You have an active sexually transmitted infection (unless treated) - You have had your cervix surgically removed - You have a history of cervical cancer - You have been fully vaccinated against HPV (all recommended doses) Talk to your doctor to see if this trial is right for you.