The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

This study is exploring how the gut microbiome (the community of bacteria living in the digestive system) affects blood sugar control in young people with Type 1 Diabetes, and how the medication metformin might play a role. Researchers hope to better understand the connection between gut health and diabetes management in teenagers. **You may be eligible if...** - You are between 11 and 18 years old - You have Type 1 Diabetes - You are either overweight/obese OR lean/normal weight **You may NOT be eligible if...** - You have a rare genetic form of diabetes or Type 2 Diabetes - You have had an infection or taken antibiotics in the past month - You have a weakened immune system or have taken steroids or immune-suppressing medications in the past 6 months - You have a chronic digestive condition - You are pregnant or planning to become pregnant - You use tobacco, cannabis, or recreational drugs - You take probiotics or have had weight loss surgery Talk to your doctor to see if this trial is right for you.