RecruitingNCT05415631

Augmented Bladder Tumor Detection Using Real Time Based Artificial Intelligence

Augmented Bladder Tumor Detection Using the Bladder-Portable Artifact Detection System: A Multicentric Prospective Analytic Study Using Real Time Based Artificial Intelligence (IA).


Sponsor

Centre Hospitalier Universitaire, Amiens

Enrollment

500 participants

Start Date

May 13, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Today the standard for the diagnosis and monitoring of bladder tumors is bladder endoscopy. The performance of this exam is not perfect. With this work, based on artificial intelligence, the investigators wish to combine endoscopy with a complementary diagnostic tool in order to improve patient care. The main objective will be to reduce diagnostic errors / wanderings in patients treated or followed for bladder tumors, by imposing a new standard of diagnostic bladder mapping (high PPV and VPN, high precision)(primary purpose diagnostic). The secondary objective will be to homogenize and systematize the descriptive part of the lesions, and to use AI to better characterize tumor aggressiveness. The final objective being to validate a new precision tool (diagnostic companion) essential for developing and standardizing the therapeutic management of bladder tumors (correcting inter-observer heterogeneity). In this project, video frame will be first extracted from our dataset of cystoscopy videos hosted in in the Next Cloud Recherche. Selected medical image will be segmented and analyzed using our pre-trained CNN model with a feature detection algorithm to obtain features. Data will be analyzed on both patient and lesion levels. The study will assess the Bladder-PAD accuracy on the detection of bladder tumors, and its ability to predict tumor risk of recurrence and progression.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether artificial intelligence (AI) tools used in real time during a bladder exam (cystoscopy) can help doctors detect bladder cancer tumors more accurately. Bladder cancer can sometimes be missed during standard procedures, and AI may help spot lesions that are hard to see. **You may be eligible if...** - You have suspected bladder cancer — either a new case or a return of a previous tumor - The tumor(s) are 3 cm or smaller - You have no more than 5 suspected lesions **You may NOT be eligible if...** - You have more than 5 suspected lesions - Any individual tumor is larger than 3 cm - Your cancer has already spread beyond the bladder (muscle-invasive or metastatic) - You are pregnant - You are unable to tolerate the procedure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Amiens University Hospital

Amiens, France

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NCT05415631


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