The CROCO Study: CROhn's Disease COhort Study
GLSMED Learning Health S.A.
600 participants
Aug 1, 2021
INTERVENTIONAL
Conditions
Summary
The investigators propose to create a prospective Crohn Disease cohort, where patients receiving the most up-to-date therapies with a treat-to-target strategy, will be closely followed to characterize the progression of Crohn Disease by measuring the Lémann Index over time. The goal of the CROCO Study - "Crohn's Disease Cohort Study" is to promote a greater understanding of the long-term evolution of Crohn Disease , to describe prospectively the impact of different therapeutic strategies and develop accurate predictors of bowel disease damage and disability.
Eligibility
Inclusion Criteria4
- To be eligible all of the following criteria must be met:
- Diagnosis of CD (according to ECCO guidelines) established within the past 12 months;
- Patients able to understand the information provided to them and to give written informed consent for the study;
- Male or female, age \> 18 years.
Exclusion Criteria5
- Patients unwilling or unable to provide informed, written consent;
- Severe underlying medical disorder with an anticipated life expectancy \< 2 years;
- Refusal or medical conditions (e.g. Glomerular filtration rate \< 30 mL/min) preventing cross-sectional imaging during follow-up;
- Uncertain CD diagnosis;
- Pregnancy (if it is impossible to implement the MRE at one year) or any other reason that makes resonance not feasible throughout the study (eg claustrophobia).
Interventions
Magnetic Resonance Enterography at year 1 (in some patients)
Locations(20)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05420233