RecruitingNot ApplicableNCT05420766

Impact of Sleep Duration on Immune Balance in Urban Children With Asthma


Sponsor

Rhode Island Hospital

Enrollment

204 participants

Start Date

May 15, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes both sleep and asthma management. Further, urban children with asthma suffer from altered immune balance, a key biological process contributing to individual differences in asthma morbidity and sleep health. In the proposed research, the researchers will examine the effects of shortened and recovery sleep on immune balance and associated changes in lung function in urban children with allergic asthma through an experimental design.


Eligibility

Min Age: 7 YearsMax Age: 11 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating how sleep duration affects the immune system in children with asthma who are allergic (atopic). Researchers believe that getting too little or too much sleep may change immune cell behavior, which could worsen asthma symptoms. This is an observational study — no new treatments are given. **You may be eligible if...** - Your child is between 7 and 11 years old - Your child has been diagnosed with asthma by a doctor - Your child has persistent asthma requiring a daily controller medication - Your child gets between 9 and 11 hours of sleep per day - Your child has a positive allergy test (to dust mites, mold, or cockroach) - You and your child live in an urban area **You may NOT be eligible if...** - Your child has a serious immune system disorder - Your child has significant other health conditions (e.g., heart or lung disease unrelated to asthma) - Your child uses medications that affect the immune system (like steroids) - Your child regularly gets much less or more sleep than the study range Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALShortened Sleep

In this experimental condition, children go to bed 90 minutes later than their typical bedtime during Week 2 of the 4-week protocol.

BEHAVIORALStabilized sleep

In this control condition, children go to bed at their usual time throughout the 4-week protocol.


Locations(1)

Rhode Island Hospital

Providence, Rhode Island, United States

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NCT05420766


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