Early vs Delayed Surgery for Stricturing CD--a RCT

This study is comparing surgery versus biologic medications (targeted immune therapies) for people with Crohn's disease who have developed a narrowing (stricture) in the intestine that is blocking normal digestion. Both approaches are used in practice, and this trial aims to determine which leads to better outcomes. **You may be eligible if...** - You have Crohn's disease with confirmed intestinal narrowing (stricture) causing bowel obstruction symptoms - You have active bowel inflammation alongside the stricture - Standard medications (like steroids or immunomodulators) have not worked - The stricture cannot be safely treated with endoscopic balloon dilation (EBD) - You are willing and able to provide written consent **You may NOT be eligible if...** - Your stricture can be managed with endoscopic dilation - You have a bowel perforation, fistula, or abscess requiring urgent surgery - You have a serious infection or other condition making surgery or biologic treatment unsafe - You are pregnant Talk to your doctor to see if this trial is right for you.