Neural Connectivity During Therapy for Adolescent PTSD

This research study is looking at how the brain's connections change during therapy for PTSD in teenagers. Participants will receive a trauma-focused therapy called TF-CBT and also undergo brain MRI scans so researchers can track changes in brain activity over the course of treatment. **You may be eligible if:** - You are between 12 and 17 years old (and at Tanner Stage 2 or above, meaning you have entered puberty) - You have experienced interpersonal trauma (e.g., abuse, assault, or violence) - You have significant PTSD symptoms from at least one symptom in each of the four PTSD clusters for at least one month **You may NOT be eligible if:** - You are currently taking or have previously taken psychiatric medications - You have severe suicidal or homicidal thoughts - You are currently hospitalized - You are currently in other psychotherapy or have previously received TF-CBT - You have had a head injury with loss of consciousness lasting more than 5 minutes - Your IQ is below 85 - You have braces or metal in your body (MRI-incompatible) - You have psychosis, bipolar disorder, autism, or panic disorder - You have used substances frequently in the past 3 months Talk to your doctor to see if this trial is right for you.