Ablative Carbon Ion Radiotherapy With Pencil Beam Scanning for Locally Advanced Unresectable Pancreatic Cancer

This study is testing a highly precise form of radiation therapy called carbon ion radiotherapy for people with locally advanced pancreatic cancer that cannot be surgically removed. Carbon ion beams can target tumors more precisely than conventional radiation, potentially causing less damage to nearby organs. **You may be eligible if:** - You are at least 18 years old - You have pancreatic cancer confirmed by biopsy (ductal adenocarcinoma) - Your cancer has not spread to distant organs but cannot be surgically removed (Stage III) - Your tumor is 7 cm or smaller - The tumor has not grown into your stomach, duodenum, or small intestine - You are in reasonably good health (ECOG 0–1) - Your blood counts, liver, and kidney function are within acceptable ranges **You may NOT be eligible if:** - You have multiple tumors in the pancreas - The tumor has invaded the digestive tract directly - You have had prior radiation therapy or other local treatments for pancreatic cancer - You have had another cancer previously - You cannot understand or consent to the treatment Talk to your doctor to see if this trial is right for you.