RecruitingPhase 3NCT05430620

Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys

A Prospective Feasibility Trail to Compare the Efficacy of Intermittent Surface Oxygenation With Continuous Surface Oxygenation During Hypothermic Machine Perfusion of Kidneys Donated After Circulatory Death


Sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Enrollment

60 participants

Start Date

Mar 20, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of the study is to evaluate the feasibility of this bubble and surface oxygenation and to determine the optimal timing of surface oxygenation (continuous versus intermittent) as alternative for membrane-oxygenated kidneys, originating from DCD donors, during HMP on early graft function in clinical practice.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Listed for a renal transplantation due to end stage renal disease
  • Willingness to comply with the protocol procedures for the duration of the study included scheduled follow-up visits and examinations.

Exclusion Criteria2

  • Multi-organ recipients
  • Dual kidney transplantation

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Interventions

DRUGOxygen

Active oxygenation during hypothermic machine perfusion by bubble and surface oxygenation. Intermittent surface oxygenation is compared with continuous surface oxygenation during hypothermic machine perfusion


Locations(1)

Cliniques Universitaires Saint-Luc

Brussels, Woluwé-Saint-Lambert, Belgium

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NCT05430620


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