RecruitingPhase 2Phase 3NCT05431595

Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy


Sponsor

M.D. Anderson Cancer Center

Enrollment

42 participants

Start Date

Jul 19, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

To examine the effects of haloperidol, chlorpromazine, valproic acid and placebo, in conjunction with standardized non-pharmacologic interventions, in the first line treatment of agitated delirium in hospitalized patients with cancer. This double-blind, randomized clinical trial aims to provide evidence on various therapeutic options for palliating delirium, thereby reducing delirium-related distress and ultimately alleviating suffering.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Chlorpromazine, a drug called Haloperidol, and others for people with delirium, epileptics, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGHaloperidol

Given by Vein (IV)

DRUGChlorpromazine

Given by Vein (IV)

DRUGValproate

Given by Vein (IV)

DRUGPlacebo

Given by Vein (IV)


Locations(1)

MD Anderson Cancer Center

Houston, Texas, United States

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NCT05431595


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