RecruitingPhase 4NCT05435547

Preoperative Corticosteroids in Autoimmune Thyroid Disease

Randomized Controlled Trial of Preoperative Corticosteroids in Autoimmune ThyroidDisease

Sponsor

Indiana University

Enrollment

76 participants

Start Date

Jun 16, 2023

Study Type

INTERVENTIONAL

Conditions

Graves Disease Hashimoto Disease

Summary

This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of the gland and makes surgery less difficult.

Eligibility

Min Age: 18 Years

Inclusion Criteria1

■ Graves' disease or Hashimoto's disease with positive thyroid autoantibodies (TgAb, TPO, TSI, and/or TRAb) undergoing total thyroidectomy for their disease.

Exclusion Criteria7

Pediatric patients < 18
Prior treatment with RAI
Prior neck surgeries
Known diagnosis of thyroid cancer
Diabetic patients on medications
A history of adverse reactions to corticosteroids.
Patients on any immunosuppressive regimen (such as organ transplant patients or patients treated for other autoimmune conditions). This includes patients with recent history of steroid therapy, or a history of adverse reactions to corticosteroids.

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