RecruitingPhase 4NCT05435547
Preoperative Corticosteroids in Autoimmune Thyroid Disease
Randomized Controlled Trial of Preoperative Corticosteroids in Autoimmune ThyroidDisease
Sponsor
Indiana University
Enrollment
76 participants
Start Date
Jun 16, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of the gland and makes surgery less difficult.
Eligibility
Min Age: 18 Years
Inclusion Criteria1
- ■ Graves' disease or Hashimoto's disease with positive thyroid autoantibodies (TgAb, TPO, TSI, and/or TRAb) undergoing total thyroidectomy for their disease.
Exclusion Criteria7
- Pediatric patients \< 18
- Prior treatment with RAI
- Prior neck surgeries
- Known diagnosis of thyroid cancer
- Diabetic patients on medications
- A history of adverse reactions to corticosteroids.
- Patients on any immunosuppressive regimen (such as organ transplant patients or patients treated for other autoimmune conditions). This includes patients with recent history of steroid therapy, or a history of adverse reactions to corticosteroids.
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Interventions
DRUGDexamethasone
Will take Dexamethasone pre-operatively
DRUGPlacebo
Will take Placebo pre-operatively
Locations(3)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05435547
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