RecruitingNot ApplicableNCT05444478

Microwave Ablation Simultaneously Combined With Lenavatinib for Recurrent Hepatocellular Carcinoma

Microwave Ablation Simultaneously Combined With Lenavatinib for Recurrent Hepatocellular Carcinoma: a Prospective Randomized Controlled Study


Sponsor

Sun Yat-sen University

Enrollment

274 participants

Start Date

Jul 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This study intends to evaluate the efficacy and safety of microwave ablation combined lenvatinib simultaneously for recurrent HCC


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether combining microwave ablation (a procedure that uses heat to destroy tumors) with lenvatinib (a targeted drug) is more effective than ablation alone for treating recurrent liver cancer (HCC). **You may be eligible if...** - You have primary liver cancer (HCC) that has come back after prior treatment - You have 3 or fewer tumors, each no larger than 5 cm - You are between 18 and 75 years old - Your liver function is preserved (Child-Pugh A or mild B) - Your blood counts and organ function are within acceptable ranges - Your overall health is good (KPS score 90 or above) **You may NOT be eligible if...** - Your cancer has spread into major blood vessels or outside the liver - You have had a prior different cancer - You are unwilling to participate in follow-up - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREMicrowave ablation

only microwave ablation for tumor

DRUGLenvatinib

lenvatinib (80 mg for body no more than 60kg,120 mg for body weight \>60 kg)


Locations(1)

Hunan Provincial People's Hospital

Changsha, Hunan, China

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NCT05444478


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