RecruitingNCT05444920

The Italian Transthyretin Amyloidosis Web-Network

The Italian Transthyretin Amyloidosis Web-Network (ITA-WebNet)


Sponsor

Fondazione IRCCS Policlinico San Matteo di Pavia

Enrollment

1,000 participants

Start Date

Jul 13, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The study aims, by generating a large registry of patients with ATTR amyloidosis, including data at diagnosis and during follow up, to describe the natural history of ATTR amyloidosis in a real-world setting and to define and validate prognostic models, response criteria applicable at any point of the disease. The registry will also be used for data sharing and to allow the possibility of a close collaboration amongst the amyloidosis experts of the ARTC and all the physicians around the Country involved in the diagnosis and management of systemic amyloidosis. Thanks to the online registry, the diagnostic facility of the ARTC will be made available to requesting physicians.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This study is building a national web-based registry (database) of patients in Italy who have been diagnosed with, or are suspected to have, transthyretin amyloidosis (ATTR) — a disease where an abnormal protein called transthyretin misfolds and deposits in organs like the heart, nerves, and kidneys. By collecting long-term data on these patients, researchers hope to better understand the disease and improve future treatments. You may be eligible if: - You are 18 years old or older - You have a suspected or confirmed diagnosis of systemic or localized amyloidosis (any type except AL) - You are receiving follow-up care at a participating center - You are willing to sign informed consent You may NOT be eligible if: - You have been diagnosed specifically with AL (light-chain) amyloidosis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(30)

ASST Ovest Milanese - Ospedale di Legnano

Legnano, MI, Italy

AOU San Luigi Gonzaga

Orbassano, TO, Italy

AOU Ospedali Riuniti

Ancona, Italy

Policlinico di Bari

Bari, Italy

ASST Papa Giovanni XXIII

Bergamo, Italy

ASST Spedali Civili di Brescia

Brescia, Italy

Ospedale Oncologico "Armando Businco"

Cagliari, Italy

Azienda Ospedaliera di Cosenza

Cosenza, Italy

Presidio ospedaliero di Ivrea

Ivrea, Italy

Asst Santi Paolo E Carlo

Milan, Italy

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Italy

IRCCS Istituto Clinico Humanitas

Milan, Italy

Istituto Auxologico Italiano

Milan, Italy

Istituto Monzino

Milan, Italy

IRCCS San Gerardo Monza

Monza, Italy

'Azienda Ospedale. Università di Padova

Padova, Italy

Fondazione IRCCS Policlinico San Matteo

Pavia, Italy

Azienda Ospedaliera di Perugia

Perugia, Italy

Ospedale Civile ASL Pescara

Pescara, Italy

Azienda Ospedaliera Sant'Andrea

Roma, Italy

Ematologia ASL Roma 1

Roma, Italy

Fondazione Policlinico Universitario Agostino Gemelli CARDIOLOGIA

Roma, Italy

Policlinico Universitario Agostino Gemelli NEUROLOGIA

Roma, Italy

Plesso Ospedaliero "Andrea Tortora" di Pagani

Salerno, Italy

Azienda Ospedaliero Universitaria di Sassari

Sassari, Italy

Azienda Ospedaliero Universitaria Senese

Siena, Italy

Ospedale San Giovanni Bosco

Torino, Italy

l'Ospedale di Treviglio-Caravaggio

Treviglio, Italy

Osp. Sant'Andrea

Vercelli, Italy

Azienda Ulss 8 Berica

Vicenza, Italy

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NCT05444920


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