RecruitingPhase 2NCT05445310

Adjuvant Furmonertinib in Stage IA With High Risk Factors and Stage IB Non-small Cell Lung Cancer

Adjuvant Furmonertinib in Stage IA With High Risk Factors and Stage IB Non-small Cell Lung Cancer: a Prospective Single-arm Study


Sponsor

Peking Union Medical College Hospital

Enrollment

114 participants

Start Date

Aug 6, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective, single arm study to investigate the efficacy and safety furmonertinib 80mg/d as adjuvant treatment for 3 years post surgery of stage IA with high-risk factors and stage IB non-small cell lung cancer. A total of 114 patients would be enrolled. The primary endpoint is the disease-free survival rate at 3 years.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing furmonertinib, a targeted drug for lung cancer with specific gene mutations, as a follow-up treatment (adjuvant therapy) after surgery in people with early-stage non-small cell lung cancer (NSCLC) that has specific high-risk features. **You may be eligible if...** - You have had surgery to remove your lung cancer - You have been diagnosed with non-small cell lung cancer (confirmed by two pathologists) - Your cancer is stage IA with high-risk features OR stage IB - Your cancer has a specific EGFR gene mutation confirmed by genetic testing - Your overall health is good **You may NOT be eligible if...** - You received any cancer treatment before surgery - Your cancer does not have an EGFR mutation - You have significant organ dysfunction or immune conditions - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGFurmonertinib

Furmonertinib 80mg/d


Locations(1)

Peking Union Medical College Hopital

Beijing, China

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NCT05445310


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