RecruitingPhase 3NCT05460416

Treatment Preventive for Pre-eclampsia by Acetylsalicylic Acid in Women Who Underwent Frozen Embryo Transfer

A Prospective Interventional Randomized Controlled Trial to Assess the Effect of Low Dose Acetylsalicylic Acid As a Preventive Treatment of Pre-eclampsia in Pregnant Women Who Underwent Frozen Embryo Transfer


Sponsor

Centre Hospitalier Universitaire de Liege

Enrollment

276 participants

Start Date

Oct 25, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Title: A prospective multicentric interventional randomized controlled trial to assess the effect of low dose acetylsalicylic acid as a preventive treatment of pre-eclampsia in pregnant women who underwent frozen embryo transfer


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 43 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether taking low-dose aspirin during a frozen embryo transfer (FET) pregnancy can help prevent preeclampsia — a dangerous high blood pressure condition that can develop during pregnancy. Researchers are specifically looking at women who conceived through assisted reproduction, where preeclampsia risk may be higher. **You may be eligible if...** - You are a healthy woman aged 18–43 - You are undergoing a frozen embryo transfer cycle (natural, modified natural, or hormone replacement cycle) - You have a confirmed pregnancy at 6 weeks of pregnancy - You have given informed consent **You may NOT be eligible if...** - You already have a known risk factor for preeclampsia (e.g., history of preeclampsia, certain medical conditions) - You have an allergy to aspirin or anti-inflammatory drugs - You have a bleeding disorder or other condition making aspirin unsafe Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAcetylsalicylic acid

160mg once a day


Locations(1)

Centre Hospitalier Universitaire de Liège site Citadelle

Liège, Belgium

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NCT05460416


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