RecruitingPhase 3NCT07499817

Effect of Pentoxyfilline on Endometrial Thickness and Frozen Embryo Transfer Outcomes

Sponsor

Beni-Suef University

Enrollment

100 participants

Start Date

Oct 1, 2023

Study Type

INTERVENTIONAL

Conditions

Infertility IVF Embryo Transfer

Summary

The aim of this work was to investigate the effect of different vasodilators as pentoxifylline in women with unexplained infertility using IVF

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 43 Years

Inclusion Criteria1

as good quality day five frozen embryos.

Exclusion Criteria3

history of endocrine diseases,
history of any previous surgery that couldm compromise the integrity of endometrium,
cardiovascular, renal and liver diseases,

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Interventions

DRUGpentoxifylline 400 mg

Once daily in form of (Trental ® Sanofi co.) daily in addition to the above treatment protocol from the first day of the cycle until the day of starting progesterone.

OTHER(control)

estradiol valerate 2 mg. in form of (Cycloprogynova® Bayer Shering Pharma) whitepills starting dose is one pill T.I.D

Locations(1)

Beni-suef university Hospital

Banī Suwayf, Beni Suweif Governorate, Egypt

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NCT07499817

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