RecruitingNCT05462366

Omics Sequencing of Specimen Derived From Mother-Infant-Pairs


Sponsor

Zhujiang Hospital

Enrollment

100 participants

Start Date

Jun 22, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The investigators aim to collect breast-milk and feces from the participants, and apply culture techniques as well as omics sequencing technology to probe into the microbial and metabolomic signature of the specimens.


Eligibility

Max Age: 40 Years

Inclusion Criteria4

  • healthy pregnant women aged between 20y and 40y.
  • Vaginal birth
  • BMI<23.5 before pregnancy
  • Infants' birth weight, between 2500g and 4000g.

Exclusion Criteria7

  • gestational diabetes
  • diagnosis of depressive disorder during pregnancy
  • gestational hypertension
  • diagnosis of other diseases during pregnancy
  • Under probiotics or antibiotic treatment from 3 months prior to pregnancy till 3 months after delivery
  • histrory of smoking and drinking alcohol
  • history of diarrhea from 3 months prior to pregnancy till 3 months after delivery

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Interventions

OTHERSample collection

Collect breast-milk and feces from mother-infant-pairs.


Locations(1)

Zhujiang Hospital

Guangzhou, Guangdong, China

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NCT05462366


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