RecruitingNCT05468905

China Longitudinal Aging and Cognitive Impairment Study

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Enrollment

4,000 participants

Start Date

Jan 10, 2021

Study Type

OBSERVATIONAL

Conditions

Alzheimer Disease Aging Mild Cognitive Impairment Neurodegeneration

Summary

This is a multi-center longitudinal study that consists of five cohorts: cognitive normal aging (CN), Subjective cognitive impairment (SCI), mild cognitive impairment (MCI), Alzheimer's disease (AD) and vascular cognitive impairment (VCI). The goals of this study are as follow: 1.To establish longitudinal cohort study database containing comprehensive epidemiological data, neuropsychological test data, laboratory parameters, image data and biological samples. 2. To determine the risk factors of AD and other dementias. 3. To explore the conversion rates from CN to SCI, MCI or AD and the risk factors as well as biomarkers for the progression from CN to SCI, MCI or AD. 4. To explore and validate blood, CSF, urine, imaging and other biomarkers for the early detection and progression of AD.

Eligibility

Min Age: 40 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This is a long-term study in China following older adults over time to better understand how aging, lifestyle, and health factors contribute to memory loss and cognitive decline (such as Alzheimer's disease and dementia). **You may be eligible if...** - You are an older adult living in China - You are willing to participate in cognitive tests, health assessments, and follow-up visits over multiple years - You may or may not have early signs of memory or thinking problems **You may NOT be eligible if...** - You are unable or unwilling to complete regular study assessments - You have a condition that makes cognitive testing unreliable Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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