RecruitingNCT05473637

Taiwan Associated Genetic and Nongenetic Small Vessel Disease

Deciphering, Construction and Validation of Magnetic Resonance Imaging Maps, Clinical Features and Outcomes in Genetic and Nongenetic Cerebral Small Vessel Diseases


Sponsor

National Taiwan University Hospital

Enrollment

500 participants

Start Date

Jan 1, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

The TAG-SVD enrolled patients with clinical and neuroimaging features of cerebral small vessel disease (CSVD). All enrolled patients will receive next-generation sequence (NGS) with probes designed to target five candidate CSVD genes, and patients will be divided into genetic or non-genetic groups accordingly. Their clinical features and outcome will be followed for at least 2 years.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying MRI for people with col4a1-related brain small vessel disease with haemorrhage, cadasil, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTMRI

Patients will repeat study-protocol MRI at baseline (enrollment) and at least once in 1 year or 2 years follow-up (depends on availability).


Locations(1)

Department of Neurology, National Taiwan University Hospital

Taipei, Taiwan

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NCT05473637


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