Cadasil Clinical Trials

12 recruitingLast updated: June 18, 2026

There are 12 actively recruiting cadasil clinical trials across 9 countries. Studies span Not Applicable. Top locations include Los Angeles, California, United States, Milan, Italy, Chicago, Illinois, United States. Updated daily from ClinicalTrials.gov.


Cadasil Trials at a Glance

12 actively recruiting trials for cadasil are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 1 trial, with the heaviest enrollment activity in Los Angeles, Milan, and Chicago. Lead sponsors running cadasil studies include Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Children's Hospital of Philadelphia, and Bin Cai.

Browse cadasil trials by phase

Treatments under study

About Cadasil Clinical Trials

Looking for clinical trials for Cadasil? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cadasil trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cadasil clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting

Natural History Study of CADASIL

Arterial StiffnessCardiovascular DiseaseGermline Mutation in the NOTCH 3 Gene+2 more
National Heart, Lung, and Blood Institute (NHLBI)155 enrolled1 locationNCT05072483
Recruiting

Long-term Prospective Study of Korean CADASIL Patients

CadasilCerebral Autosomal Dominant Arteriopatie With Subcortical Infarcts and Leukoencephalopathy
Jeju National University Hospital500 enrolled1 locationNCT07497867
Recruiting

RAre, But Not aLone: a Large Italian Network to Empower the Impervious diaGNostic Pathway of Rare cerEbrovascular Diseases (ALIGNED)

Fabry DiseaseCadasilMoya Moya Disease+5 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta500 enrolled17 locationsNCT06935578
Recruiting

Taiwan Associated Genetic and Nongenetic Small Vessel Disease

StrokeMagnetic Resonance ImagingFabry Disease+5 more
National Taiwan University Hospital500 enrolled1 locationNCT05473637
Recruiting

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

Cadasil
University of Wisconsin, Madison660 enrolled12 locationsNCT05677880
Recruiting

The Myelin Disorders Biorepository Project

AdrenoleukodystrophyCockayne SyndromeRefsum Disease+63 more
Children's Hospital of Philadelphia12,000 enrolled23 locationsNCT03047369
Recruiting
Not Applicable

Neurologic Stem Cell Treatment Study

Cognitive ImpairmentDementiaTraumatic Brain Injury+23 more
MD Stem Cells500 enrolled3 locationsNCT02795052
Recruiting

Genotype, Clinical Features and Imaging of Neuroradiological Abnormalities in CADASIL

CadasilCADASIL (Diagnosis)
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta100 enrolled2 locationsNCT06938100
Recruiting

AusCADASIL: An Australian Cohort of CADASIL

Cadasil
Perminder Sachdev300 enrolled5 locationsNCT06148051
Recruiting

CADASIL Registry Study

Cadasil
Bin Cai1,000 enrolled1 locationNCT04310098
Recruiting

MRI Study of Blood-brain Barrier Function in CADASIL

CadasilBlood Brain Barrier Defect
Peking University First Hospital100 enrolled1 locationNCT05902039
Recruiting

Prognosis of Cerebral Small Vessel Disease

Cerebral Amyloid AngiopathyCadasilSmall Vessel Cerebrovascular Disease+1 more
Insel Gruppe AG, University Hospital Bern900 enrolled1 locationNCT05734378