RecruitingPhase 2NCT05475171
Triage of Advanced Cervical Cancer Through Immunotherapy Induction (TRACTION)
Sponsor
M.D. Anderson Cancer Center
Enrollment
40 participants
Start Date
Dec 13, 2022
Study Type
INTERVENTIONAL
Conditions
Summary
To learn if MGD019 can help to control cervical cancer in patients who have yet to receive treatment.
Eligibility
Min Age: 18 Years
Plain Language Summary
Simplified for easier understanding
The TRACTION study is testing an immunotherapy drug (checkpoint inhibitor) given before standard chemotherapy to see if a patient's response to this "induction" treatment can predict how well they'll respond overall, helping doctors personalize treatment for advanced or recurring cervical cancer.
**You may be eligible if...**
- You have recurrent, metastatic, or persistent cervical cancer (squamous cell carcinoma, adenosquamous, or adenocarcinoma type)
- Your cancer is not curable by surgery or radiation
- You have not previously received chemotherapy for recurrent/metastatic disease
- You are in good overall health (ECOG performance status 0–1) with adequate organ function
**You may NOT be eligible if...**
- You have already received chemotherapy for recurrent or metastatic cervical cancer
- You have a serious autoimmune disease requiring systemic treatment
- You have uncontrolled brain metastases
- You are pregnant or breastfeeding
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUGLorigerlimab
Given by vein (IV)
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05475171
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