RecruitingNCT05479617

Personalised Prediction of Disease Course in Ulcerative Colitis Using Multimodal Machine Learning - Part of the Presager Project


Sponsor

Copenhagen University Hospital, Hvidovre

Enrollment

400 participants

Start Date

Jun 20, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

In patients achieving clinical remission following a flare, artificial intelligence can reliably predict a new flare within the next 12 months utilizing clinical and objective information at day 0 and week 8. Secondary endpoints: * An artificial intelligence model's precision in predicting a new flare within 2 and 3 years * An artificial intelligence model's precision to rule out patients who will not experience a new flare within 1, 2 and 3 year


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using advanced technology — including machine learning (computer programs that learn from data) — to predict how ulcerative colitis (a chronic inflammatory bowel disease) will progress in individual patients. The goal is to personalize treatment so patients get the right level of care at the right time. **You may be eligible if...** - You have been diagnosed with ulcerative colitis for at least 1 year - You are currently experiencing a flare-up of your symptoms - You have had an endoscopy (camera exam of the colon) and tissue sample taken during this flare - You have signed the consent form **You may NOT be eligible if...** - There is reasonable doubt that your current flare is caused by something other than ulcerative colitis (such as an infection) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERDeep learning model

Use of deep learning model to predict individual patients disease course


Locations(1)

Gastrounit, medical section, Copenhagen University Hospital Hvidovre

Hvidovre, Denmark, Denmark

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NCT05479617


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