RecruitingNot ApplicableNCT05485376

Pulmonary Artery Catheter in Cardiogenic Shock Trial

The Pulmonary Artery Catheter in Cardiogenic Shock Trial


Sponsor

Tufts Medical Center

Enrollment

400 participants

Start Date

Aug 23, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The primary objective of the PACCS trial is to assess if early invasive hemodynamic assessment and ongoing management with a PAC in patients with cardiogenic shock due to acutely decompensated heart failure (AHDF-CS) is associated with lower in-hospital mortality risk compared to the current standard of care with no or delayed PAC assessment.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether using a pulmonary artery catheter — a thin tube inserted into the heart's right side to precisely measure pressure and blood flow — improves outcomes for people in cardiogenic shock (a life-threatening condition where the heart suddenly can't pump enough blood to meet the body's needs). **You may be eligible if...** - You are between 18 and 90 years old - You have acute (sudden) heart failure with cardiogenic shock and your heart's pumping function (ejection fraction) is 40% or lower - You have dangerously elevated blood lactate levels and at least two signs of shock (very low blood pressure, need for medications to support blood pressure, or signs of fluid buildup) - Your shock started within 24 hours before screening - You or your legally authorized representative can provide consent **You may NOT be eligible if...** - Your heart failure and shock does not meet the specific criteria above - Your ejection fraction is above 40% - Your shock has been ongoing for more than 24 hours before screening Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEPulmonary Artery Catheter

The pulmonary artery catheter (PAC) is a diagnostic instrument that enables continuous hemodynamic monitoring of cardiac filling pressures, cardiac output, and pulmonary pressures.


Locations(1)

Tufts Medical Center

Boston, Massachusetts, United States

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NCT05485376


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