Cardiogenic Shock Clinical Trials

77 recruitingLast updated: June 18, 2026

There are 77 actively recruiting cardiogenic shock clinical trials across 25 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1. Top locations include Strasbourg, France, Seoul, South Korea, Milan, Italy. Updated daily from ClinicalTrials.gov.


Cardiogenic Shock Trials at a Glance

77 actively recruiting trials for cardiogenic shock are listed on ClinicalTrialsFinder across 6 cities in 25 countries. The largest study group is Not Applicable with 21 trials, with the heaviest enrollment activity in Strasbourg, Seoul, and Milan. Lead sponsors running cardiogenic shock studies include Tufts Medical Center, Assistance Publique - Hôpitaux de Paris, and Abiomed Inc..

Browse cardiogenic shock trials by phase

Treatments under study

About Cardiogenic Shock Clinical Trials

Looking for clinical trials for Cardiogenic Shock? There are currently 72 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cardiogenic Shock trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cardiogenic Shock clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 77 trials

Recruiting

Abiomed Impella RT-DAQ - Observational Study

Cardiogenic Shock
Abiomed Inc.125 enrolled4 locationsNCT06308055
Recruiting

Cardiovascular Outcomes Registry in Cardiogenic SHOCK (COR-SHOCK)

Cardiogenic ShockCardiogenic Shock AcuteCardiogenic Shock Post Myocardial Infarction
Hospital de Santa Cruz, Portugal800 enrolled1 locationNCT07597291
Recruiting

BEAT-SHOCK Registry

Cardiogenic ShockMyocardial Infarction (MI)Acute Decompensated Heart Failure+4 more
University Hospital, Basel, Switzerland8,000 enrolled1 locationNCT07643610
Recruiting

OPTIMIZE 5.5 - Optimizing Impella 5.5 Outcomes Through Advanced Data Science

Cardiogenic ShockMechanical Circulatory SupportCardiogenic Shock Post Myocardial Infarction
Medical University of Vienna100 enrolled1 locationNCT07619144
Recruiting
Not Applicable

FEMART-1 Pilot Study

Out of Hospital Cardiac Arrest (OHCA)Sudden Cardiac ArrestCardiogenic Shock Acute
Emergency Medical Service, Prague60 enrolled1 locationNCT07596446
Recruiting

Altshock-2 REGISTRY

Cardiogenic Shock
Niguarda Hospital3,000 enrolled1 locationNCT04295252
Recruiting
Phase 1

Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO

Oxygen DeliveryCardiogenic ShockAnemia+2 more
University Hospital, Lille236 enrolled1 locationNCT05699005
Recruiting

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Intensive Care MedicineOpioid analgesiaExtracorporeal Membrane Oxygenation (ECMO)+5 more
Guy's and St Thomas' NHS Foundation Trust120 enrolled1 locationNCT07032987
Recruiting
Not Applicable

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

Cardiogenic ShockMitral Regurgitation
Ottawa Heart Institute Research Corporation144 enrolled4 locationsNCT05298124
Recruiting
Phase 2

Physiology of Unloading VA ECMO Trial

Cardiogenic Shock
University of Utah104 enrolled1 locationNCT06336655
Recruiting
Not Applicable

Transcatheter AortiC Valve Implantation in aorTic stenosIs CardiogenIc Shock

Cardiogenic ShockAortic Stenosis
Rigshospitalet, Denmark30 enrolled1 locationNCT06638268
Recruiting
Not Applicable

Early Preventive Left Ventricle Unloading After VA-ECMO for Refractory Cardiogenic Shock

Cardiogenic Shock Acute
Assistance Publique - Hôpitaux de Paris298 enrolled12 locationsNCT07027202
Recruiting
Phase 4

Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure

Heart FailureCardiogenic ShockKetone Body Metabolism+2 more
Institute for Clinical and Experimental Medicine12 enrolled1 locationNCT07527156
Recruiting
Not Applicable

Personalisation of Mean Arterial Pressure in Adult Patients With Cardiogenic Shock

Cardiogenic Shock
CMC Ambroise Paré406 enrolled11 locationsNCT07345559
Recruiting

Multimodal Phenotyping In Patients Referred With Acute Cardiac faiLurE

Cardiogenic ShockAcute Heart Failure (AHF)
University Heart Center Freiburg - Bad Krozingen600 enrolled4 locationsNCT07515508
Recruiting

Characterisation of phenotYpes in aCute Heart faiLure patiEnts

Cardiogenic ShockAcute Heart FailureDecompensated Heart Failure
Universitätsklinikum Hamburg-Eppendorf1,000 enrolled1 locationNCT07508891
Recruiting
Phase 4

Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients With Cardiogenic Shock From Acute Myocardial Infarction

Myocardial InfarctionCardiogenic Shock
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)776 enrolled1 locationNCT05168462
Recruiting

Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

Cardiogenic ShockAcute Myocardial Infarction
STAVROS G DRAKOS500 enrolled3 locationsNCT05185492
Recruiting

Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

AMI Cardiogenic Shock
Abiomed Inc.350 enrolled10 locationsNCT06964685
Recruiting

Inova Cardiogenic Shock Registry (INOVA SHOCK)

Cardiogenic Shock
Inova Health Care Services3,000 enrolled1 locationNCT03378739