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RecruitingNCT05501587

Measures of Respiratory Health Registry

Sponsor

University of British Columbia

Enrollment

1,000 participants

Start Date

Oct 11, 2018

Study Type

OBSERVATIONAL

Conditions

Cystic FibrosisRespiratory Disease

Summary

There are many techniques that can allow for the quantification of lung function in children; some are being used clinically and others are under development. Many of these tools are available at BC Children's Hospital. This registry study will act as a central repository for the results of traditional and novel pulmonary function tests done at BC Children's Hospital to allow for future analysis.

Eligibility

Min Age: 0 YearsMax Age: 99 Years

Inclusion Criteria9

  • Participants with CF
  • Diagnosis of CF as evidenced by one or more clinical feature consistent with the CF phenotype or positive CF newborn screen AND one or more of the following criteria: i. A documented sweat chloride ≥ 60 mEq/L by quantitative pilocarpine iontophoresis (QPIT).
  • ii. A documented genotype with two disease-causing mutations in the CFTR gene.
  • \- In the opinion of the investigator, the participant will likely have the ability to perform the lung function test of interest on the day of testing
  • Physician-diagnosed lung disease
  • Informed consent by participant, parent, or legal guardian
  • In the opinion of the investigator, the participant will likely have the ability to perform the lung function test of interest on the day of testing
  • Informed consent by participant, parent, or legal guardian
  • In the opinion of the investigator, the participant will likely have the ability to perform the lung function test of interest on the day of testing

Exclusion Criteria8

  • Physical findings at the screening that would compromise the safety of the participant or the quality of the data (e.g. respiratory distress or work of breathing)
  • Requirement of supplementary oxygen to maintain oxygen saturation above 95%
  • Participants with other Respiratory Disease
  • Physical findings at screening that would compromise the safety of the participant or the quality of the research data
  • Requirement of supplementary oxygen to maintain oxygen saturation above 95%
  • Healthy Participants
  • Physical findings at screening that would compromise the safety of the participant or the quality of the research data
  • Evidence of lung disease

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Locations(1)

British Columbia Children's Hospital

Vancouver, British Columbia, Canada

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NCT05501587

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