RecruitingNCT05508126

Multi-parametric MRI and Dual-energy CT in Patients of Gastric Cancer

Diagnostic Accuracy of Multi-parametric MRI and Dual-energy CT in Gastric Cancer: a Paired Validating Confirmatory Study


Sponsor

The First Affiliated Hospital with Nanjing Medical University

Enrollment

222 participants

Start Date

Nov 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Accurate preoperative staging of gastric cancer is of major importance for guiding therapeutic decision-making, preventing both under- and over-treatment. The purpose of this study is to investigate the diagnostic performance of the Multi-parametric magnetic resonance imaging (mpMRI) and dual-energy computed tomography (DECT) in gastric cancer.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Consecutive patients with preoperative pathologically confirmed GC by endoscopy and preoperative imaging data (DECT/mpMRI) were included.
  • No contraindications for CT/MRI examination
  • Written informed consent

Exclusion Criteria4

  • Patients with a history of previous therapy.
  • Patients with recurrent gastric cancer
  • Patients with a history of severe allergy to contrast agents
  • Patients with imaging artefacts affect the evaluation

Interventions

DIAGNOSTIC_TESTDECT examination

DECT examinations will be performed using a 192-slice CT scanner (SOMATOM, Force, Siemens, Forchheim, Germany).

DIAGNOSTIC_TESTmpMRI examination

The examinations were conducted on a 3-T MR scanner (MAGNETOM Skyra; Siemens Healthcare, Erlangen, Germany).


Locations(1)

Yu-Dong Zhang

Nanjing, China

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